However, identifying responsive tumor subpopulations remains a major obstacle in developing metabolism-targeted therapies, as metabolic vulnerabilities vary among cancers with different oncogene expression profiles
21,26 Multidisciplinary management Management of DRESS requires a multidisciplinary approach based on organ involvement and severity
Phase 2 trial data (NEJM, 2023) showed promising weight reduction results, but long-term safety and cardiovascular outcomes remain under investigation in ongoing Phase 3 trials
There is one case reported in the literature that demonstrated improvement in HS after initiation of liraglutide
however, they are prepared by licensed compounding pharmacies in compliance with applicable state and federal regulations
Its essential to set realistic expectations with patients and monitor both efficacy and tolerability over time