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Reduces glucagon secretion , which lowers the amount of glucose released by the liver into the bloodstream

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Adding glucagon receptor activation (Retatrutide) slightly increases effects compared to Tirzepatide but remains better than single-receptor approaches

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Our group has also previously reported on the outcomes of liraglutide whereby post-bariatric surgery patients lost a median TWL of 5.3% but discontinued, mainly due to cost [9]

While topical agents and chemical peels are the preferred methods for treating melasma, some oral treatments have been suggested as potential options