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Glutamic acid can be synthesized from oxoglutaric acid, formed in the metabolism of carbohydrates, so it does not require direct dietary sources

255 Restoring the NAD + levels via de novo biosynthesis in the liver prevents hepatic lipid accumulation and attenuates inflammation in mice on a high-fat diet (HFD)

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Two compounds hitting the same mechanism would mostly add up to a stronger version of one mechanism

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Unlike its parent molecule, Dihexa exhibits enhanced stability and improved bioavailability, allowing it to readily cross the blood-brain barrier and exert its therapeutic effects