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Exploring the potential of epigallocatechin gallate in combating insulin resistance and diabetes

Stopping GLP-1 therapy often leads to weight regain, with clinical data showing 50-70% of patients regain significant weight within 12 months post-discontinuation

Relative expression was calculated using the 2 Ct method ( Ct method

This discrepancy may be due to paxillins inherent FA targeting through the four highly conserved LIM domains at its C-terminus, which localize the protein to FAs by either direct interaction with -integrin tails or other intermediate binding partners 42

1 These results suggest that while GLP-1 weight-loss medications support significant weight loss, they dont help us maintain that weight loss when we stop taking them

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