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Each component has hundreds of independent peer-reviewed citations across decades of research

Beyond the clinical implications, the economic burden of obesity and its comorbidities are equally alarming [5, 8]

The majority of the reported events occurred in patients who experienced gastrointestinal adverse reactions leading to dehydration such as nausea, vomiting, or diarrhea [see Adverse Reactions (6)]

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Metabolism 41 , 431434 (1992)