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CharidimouAPasiMFiorelliMShamsSVon KummerRPantoniLet al
Furman et al., 2015
Redness over an involved joint (gout is highly inflammatory) Involvement of the base of the big toe on one side (the most common site for gout) Involvement of the joints at the middle of the foot Uric acid elevation on blood testing X-ray findings of swelling of joints which is not symmetrical Joint fluid is tested for infection and is negative
By addition of an organic modifier especially to the elution section of the I EC purification step, an increase in selectivity and efficiency is obtained compared to the same run with aqueous buffers, both for anion and cation exchange chromatography
The only problem, as Lorraine mentioned, is the trade-off
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