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G6PD deficiency is an X-chromosomally transmitted disorder of the erythrocyte that affects approximately 400 million people worldwide and has about 300 variants

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Front Microbiol 15

In addition to acting as a master regulator of immune responses, NF-B signaling also serves as the switch between life and death in hepatocytes in response to TNF stimulation

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This condition occurs when the body produces more reactive oxygen species (ROS) and reactive nitrogen species (RNS) than it can neutralize