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Investigations into the regulation and function of the SH2 domain-containing protein-tyrosine phosphatase, SHP-1

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Given the repression of the proneurogenic bHLH by H3K27me3, it is plausible that histone demethylases could be involved in neuronal fate determination through removal of the H3K27me3 marks and activation of pro-neurogenic bHLH factors

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