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This is because R groups are highly nonpolar

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doi: 10.1111/j.1365-2265.1995.tb01861.x

The carnitine pool as multidisease biomarker, crosstalk mediator, and therapeutic target The differences in the composition and levels of the carnitine pool in different organs reflect their unique metabolic states and health conditions, carnitine/acylcarnitine have the potential to serve as biomarkers for the occurrence and development of a variety of diseases