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Melatonin stimulates the secretion of progesterone along with the expression of cholesterol side-chain cleavage enzyme (p450scc) and steroidogenic acute regulatory protein (star) in corpus luteum of pregnant sows

Excessive ROS damages nucleic acids, proteins, and lipids to induce cell death, and sufficient intracellular GSH is critical for ROS clearance and cellular homeostasis [24,25,26,27,28,29,30]

Scientists have discovered that it has remarkable effects on gene expression, affecting thousands of genes related to healing, inflammation, antioxidant protection, and tissue remodeling

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun