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Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression

Moreover, topical application of PYC delayed the onset and reduced the incidence and multiplicity of UV-induced skin tumors in mice

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If gastrointestinal symptoms are particularly troublesome, discuss with your prescriber whether delaying dose escalation might be appropriate

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