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This selectivity represents a significant advantage of hydrogen water, as it: Targets only the most cytotoxic free radicals Doesn't interfere with beneficial oxidative processes Avoids potential antioxidant rebound effects that can occur with excessive neutralization of all ROS Supports normal cellular metabolism while protecting against oxidative damage The fundamental distinction in mechanismsenzymatic conversion by SOD versus selective neutralization by hydrogencreates different therapeutic profiles for each approach

133 In human trials, the prebiotic fibers inulin and dextrin induced reductions in serum levels of total cholesterol (-9% and -2% for inulin and dextrin, respectively), LDL cholesterol (-1 % for dextrin), and triglycerides (-21% for inulin)

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HOXC8 is a transcription factor belonging to the HOX gene family, which plays crucial roles in embryonic development and morphogenesis 33,34

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PLoS One 13 , e0203084 (2018)