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Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis

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While GHK-Cu is the copper-bound form most commonly studied in wound healing and skin regeneration, GHK-Biotin is specifically formulated to deliver the GHK peptide's follicle-stimulating properties in conjunction with biotin's structural role in keratin synthesis, making it particularly well-suited for topical scalp and hair growth applications

doi: 10.1093/jmcb/mjaa049 266 PamiesD.SartoriC.SchvartzD.Gonzlez-RuizV.PellerinL.NunesC.et al

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Endocrinology 150 , 13531360 (2009)