A separate category, including CJC-1295 and Sermorelin, works through growth-hormone stimulation instead of appetite signaling: these peptides prompt the pituitary gland to release more of the body's own growth hormone, which supports fat metabolism and helps preserve lean muscle during a calorie deficit
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Consequently, dose titration is slow and dependent on AEs, and common recommendations like reduction on food quantity or high fat or spicy food is always suggested (151, 154, 158) Also, some hypotheses might suggest that GLP-1 stimulation can affect taste perception, as it has been reported by the FDA Adverse Event Reporting System (FAERS)
doi: 10.1016/j.cmet.2006.01.004
doi: 10.3390/separations11080249