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Possible Side Effects and Risks: Before the trial begins, all potential risks and side effects will be discussed in detail

Pla2g2a inhibits the Wnt signaling by increasing YAP phosphorylation in colonic Paneth goblet cells, thereby negatively regulating the capacity of intestinal stem cells (ISCs) to form organoids (Schewe et al., 2016)

Mechanistic Hypotheses Mechanistic hypotheses focus on how the three receptor systems may interact in model systems

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