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Nature Communications (2025) 9
The +869T/C polymorphism in the transforming growth factor-beta1 gene is associated with the severity and intractability of autoimmune thyroid disease
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There are certain research works that have stated that this mostly begins because of something called molecular mimicry
14 Upon application to the skin, DHA undergoes a Maillard reaction: the carbonyl group of DHA reacts with amino acids such as arginine, histidine, and lysine in the stratum corneum to produce brown-black chromophores, known as melanoidins, which provide a brown coloration (Figure 2)
However, this process can take a long time and may be physically or emotionally difficult for both the patient and their family
