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BPC-157 does not act through a single well-characterized receptor in the way a classical small-molecule drug does

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Zhang M, Han W, Hu S, Xu H

[DOI] [PubMed] [Google Scholar] 109.Metzger F, Sajid W, Saenger S, et al

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D-Sino complexes alleviated early/acute inflammation in mouse macro-phages by inhibiting pro-inflammatory cytokines (TNF- , IL-1, CCL-3, and IL-6), effectively preventing LPS-induced NF-B activation and nuclear translocation, and targeting activated microglia in the brain injury domain, significantly reducing pro-inflammatory microglial activation (150)