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On the other hand, in case of excessive distress, cells are exposed to high levels of ROS which can cause neuroinflammation, damage to the blood-brain barrier (BBB) and impairment to astrocyte crosstalk leading to ASD (El-Ansary et al., 2018

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This process happens in two main stages

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Adeno-associated viruses as gene delivery tools for diabetic heart disease and failure: key considerations for clinicians and preclinical researchers