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Signs of kidney problems include dark or decreased urine output, swelling in legs or feet, fatigue, and difficulty concentrating

PMID: 33182553

We thus performed single-cell transcriptomic profiling experiments in young adult (23 months old (m.o.)), aged (1820 m.o.) and exenatide-treated aged (1820 m.o

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Importantly, signs of ER dysfunction identified in our proteomics dataset might contribute to broader changes in cellular function, as suggested by previous studies on glycosylation changes in chondrocytes under inflammatory stimuli, particularly involving sialic acids