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Calibration curves were prepared by spotting different amounts from respective stocks on TLC plates to achieve the final concentrations ranging from 50 to 500 ng for lupeol and 25 to 400 ng for -sitosterol
G6PD-deficient cells are unable to generate enough NADPH under the condition of severe thiol depletion and GSH biosynthesis and methionine cycle are upregulated at the expense of ATP but fail to compensate for GSH depletion (311)
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*Correspondence: Masahiro Sugimoto, [email protected] These authors share first authorship This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
