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However, this boost was temporary, returning to baseline levels after a period without coffee consumption

122,123,124 Mammalian CYPs are a family of heme-containing NAD(P)H-dependent monooxygenases that metabolize numerous endogenous metabolites, including fatty acids and steroids, and exogenous substrates, including carcinogens, pesticides and drugs, resulting in continuous production of ROS

The peptides are backed primarily by animal and cell studies, with limited high-quality evidence that theyre safe or effective in humans

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That said, if any adverse effect is suspected to be dose-related, the dose can be reduced