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Pickart, GHK-Cu has been shown to activate a plethora of remodeling-related processes including [9]: Chemoattraction of repair cells (capillary cells, mast cells, macrophages) Suppression of free radicals Release of oxidizing iron Increased protein synthesis of collagen, elastin, anti-proteases, fibroblast growth factor, and metalloproteinases

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In these studies, researchers apply GHK-Cu to standardized incisions or excisional wounds and monitor outcomes such as the rate of wound closure, re-epithelialization, granulation tissue formation, and angiogenesis