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The metabolite profiles of ME/CFS, FM, and GWS suggest that many of the altered metabolites are involved in oxidative stress, either exacerbating ROS production or depleting key antioxidant compounds needed to mitigate oxidative damage

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Dietary supplementation with 1% and 2% glycine to Phase-I HSB increased guanidinoacetate concentrations in skeletal muscle in a dose-dependent manner (Table 1)

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