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However, increasing structural and compositional complexity also introduces challenges related to batch-to-batch reproducibility, long-term biosafety, and regulatory assessment

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Hepatic metabolism contributes to BPC-157 clearance, though the peptide does not appear to undergo extensive first-pass metabolism that would completely prevent oral bioavailability

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Data synthesis and analysis In this meta-analysis, weighted mean differences (WMDs) and 95% confidence intervals (CIs) were calculated for continuous measures