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When combined with injectable biostimulators such as calcium hydroxylapatite (CaHA or Radiesse ) or poly-L-lactic acid (PLLA, SCULPTRA ), GHK-Cu enhances neocollagenesis at a cellular level

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The subsequently applied epigenome-wide screening on these samples identified differentially methylated regions (Reference Irwin, Thursby and Ondiov129) , where a high proportion of the affected genes were associated with brain function as shown by examination through gene ontology analysis (Reference Ondiov, Irwin and Thursby130)