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The authors also reported a median PFS (10.2 versus 2.8 months) in those with versus without irAEs [68]

It affects 9 million Americans, yet fewer than one in three patients is getting the treatment they need

While previous scRNA-Seq studies have focused primarily on cell heterogeneity (32, 33), we found that both cells and cells exhibit pronounced heterogeneity that is driven, at least in part, by transcriptomic differences in cell maturity

This improves confidence in research conclusions