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Both patients with AD and disease models exhibit significant downregulation of LONP1 expression in brain tissues, accompanied by dysregulation of mitochondrial protein homeostasis networks

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and (iii) inhibition is exerted by binding to the NADP + -TGR(H) reduced species

In summary, the carnitine pool is involved in a variety of biological pathways, and maintaining the homeostasis of the carnitine pool helps to enhance the coordination of cell functions so that cells can respond more effectively to changes in the internal and external environments and enhance the adaptability of the body to environmental changes

Mechanisms Studied No receptor for DSIP has been identified

Moreover, cysteines anti-inflammatory properties extend to the overall modulation of immune cells