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The oral capsule format is designed for gastrointestinal pharmacology studies investigating local GI effects (gastric ulcer models, IBD models) and systemic bioavailability via the oral route

of India (Grant No 4(5)2019 ITEA) for funding this project

10.1042/bj2750199 110 LandryR

In addition, since mitochondrial dysfunction leads to the activation of apoptosis, SIRT1 can directly regulate the apoptotic process by modulating acetylation of PGC-1 (Zhang et al., 2019)

Such targeted delivery strategies offer the prospect of minimizing drug dosages with adverse effects while maximizing research impact, opening a new area of investigation in precision approaches for diverse disease states