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A pro-liposome has the potential to become a liposome when exposed to water, forcing the phospholipids to immediately congregate by natural hydrophobic forces into a bi-layer as described above
& Linder, M
And this, I think, of course, there are many ways that you might've been able to extend the half-life, but you were starting with a hormone, a natural hormone neurotransmitter that had such an exquisitely short half-life of basically second or minutes rather than that you could give for a week
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Chen M, Zhou P, Kong Y, Li Jr, Li Y, Zhang Y, et al