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Misuse may include: taking higher doses than prescribed using medication without a prescription crushing or altering the medication combining it with other substances Possible risks of stimulant misuse include: heart problems anxiety and agitation insomnia dependency substance use disorders Because stimulant medications increase dopamine levels in the brain, they can produce reinforcing effects when misused

In Eli Lilly's pivotal Phase 3 ATTAIN clinical trialsthe studies that led to FDA approvalparticipants taking orforglipron achieved average body weight reductions of approximately 7.9% to 8.7% over 36 to 40 weeks, depending on the dosing

Sleep quality matters as much as quantity

Whilst these medications offer significant benefits when combined with lifestyle changes, questions persist about potential adverse effects, including pancreatitis

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