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Use of SAXENDA for this indication is supported by a 56-week double-blind, placebo-controlled clinical trial in 251 pediatric patients aged 12 to 17 years, a pharmacokinetic study in pediatric patients, and studies in adults with obesity [see Clinical Pharmacology (12.3), Clinical Studies (14.1, 14.2)]

These data demonstrate that ROS generated in endometriosis is largely responsible for the adverse effect of the endometriotic microenvironment on gamete and embryo quality

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