Recent evidence reveals that classical forms of programmed cell death (PCD)including autophagy, apoptosis, pyroptosis, necroptosis, and ferroptosisinteract through key nodes such as neuroinflammation, mitochondrial dysfunction, and oxidative stress
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Linus Pauling Institute Oregon State University Reviewed in June 2024 by: Elizabeth N
Glutamine metabolism and drug resistance Glutamine plays a pivotal role in the progression of tumors, and the strategic limitation of its availability is emerging as a potential therapeutic approach
Cell J 19:1117 Bains JS, Shaw CA (1997) Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death
Despite all these advancements and promising new treatments, the WHO report states,"Overall, the clinical pipeline and recently approved antibiotics are insufficient to tackle the challenge of increasing emergence and spread of antimicrobial resistance. Thus, persistent research is necessary to enhance available therapeutic options against the rising MDR infection risk