fda semaglutide shortage update from https://www.accessdata.fda.gov/ website : r/Semaglutide FDA reports adverse effects of

These results are the highest reported for any obesity medication in clinical trials to date

Headaches or Flushing: Some subjects report mild to moderate headaches, which may be related to fluctuations in GH and blood flow

402:613-626 [PubMed: 37385275] 396

Drug hypersensitivity Drug hypersensitivity is an exaggerated immune response to a medication that may not necessarily involve an allergy

References to evidence of weight regain after stopping treatment often reinforce this perspective, although sentiment varies widely based on personal experience, cost, and access

Starting at a low dose (2.5mg with T10) and gradually increasing every 4 weeks helps minimize these effects