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We have not found infrequently missed doses to be problematic for the objective of long-term weight management, although results may temporarily reduce as semaglutide levels decrease

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Additionally, rapid weight losswhile therapeutically beneficialcan potentially cause fatigue that patients might interpret as difficulty breathing, though evidence for this specific connection is limited

Clinical guidance consistently identifies dietary fiber and adequate hydration as primary first-line strategies for managing constipation in GLP-1 users

doi: 10.1016/S0140-6736(23)01185-6 7 WhartonSAronneLJStefanskiAAlfarisNFCiudinAYokoteKet al