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These medications include semaglutide (marketed as Ozempic for diabetes and Wegovy for weight management), liraglutide (Victoza for diabetes and Saxenda for weight management), dulaglutide (Trulicity for diabetes), and tirzepatide (Mounjaro for diabetes), which combines GLP-1 action with glucose-dependent insulinotropic polypeptide (GIP) receptor agonism

Hansoh Pharma has granted Merck an exclusive global license to develop, manufacture and commercialize HS-10535

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Acknowledgements This paper received financial support from the Foundation of Chengdu Medical College and the Chengdu Seventh Hospital Clinical Science Research innovation team (2022LHTD-04)

The numbers below come from preclinical scaling and from doses reported in practitioner and research-community settings