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The 28-day guideline is based on accelerated stability testing showing that peptides maintain at least 90% of original potency during that window under ideal refrigerated conditions

Lyophilized powder is more stable because removing water eliminates the aqueous environment where oxidation occurs most readily

The results of the sensitivity analysis are presented in Supplementary Figure S4

The active ingredient in Ozempic is semaglutide, a GLP-1 receptor agonist that mimics a naturally occurring hormone to improve blood sugar control in adults with type 2 diabetes

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Nguyen, R