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KPV has also been shown in non-human studies to support healthy immune modulation

Demographics and baseline characteristics were generally similar among the renal function groups (Table 1)

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139 Table 3

However, high-quality safety data in NAFLD populations are limited, and you should consult your GP or hepatologist before starting supplementation to ensure it is appropriate for your individual circumstances and does not interact with any medications you are taking

Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]