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However, randomized controlled trials of only oral thiamin supplementation have not found any benefit in CHF patients

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435 These modalities, characterized by their simplicity, maturity, and adaptability, provide a promising avenue for emerging targets

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Hibberd MC, Wu M, Rodionov DA, Li X, Cheng J, Griffin NW, Barratt MJ, Giannone RJ, Hettich RL, Osterman AL et al (2017) The effects of micronutrient deficiencies on bacterial species from the human gut microbiota