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Novo Nordisk is currently progressing eleven drug candidates through clinical development, the most advanced of which are NN-9932 (semaglutide), CagriSema (cagrilintide + semaglutide), and cagrilintide, and are either in pre-registration or Phase III clinical trials (Table 2)

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Acknowledgments All graphical illustrations in this work were prepared using BioRender ( Conflict of interest The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest

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In addition to microglia, astrocytes and peripheral immune cells can also contribute to neuroinflammatory processes