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Similar to obese patients, patients with Cushings syndrome also responded with supranormal IGF-I levels following administration of exogenous GH (95, 103)

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He went on to conclude that even though the presence of senile plaques and neurofibrillary tangles were observed, the plaques are not the cause of senile dementia, but only an accompanying feature of senile involution of the central nervous system [7]

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