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Obes Surg (2012) 22(4):5826

Abstract Background

In an experimental study carried out by Chen Y et al., 2018, it was determined that, in Sprague Dawley rats fed a High fat diet (HFD) during 12 weeks, the authors demonstrated that APS1 significantly reduced body weight and also reduced the accumulation of hepatic lipids regulating the expression of SIRT-1/PGC-1/SREBP-1, as well as the increase in hepatic antioxidant activity on modulating the expression of activity of NRF-2 and HO-1 [51]

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(2002) Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin

Neurosci Biobehav Rev 71, 294312