Definitive evidence of the role of FFAs in GH-mediated insulin resistance was obtained in clinical studies in which the effects of exogenously administered GH on insulin resistance were abrogated by Acipimoxan inhibitor of lipolysis [185, 190, 191]
Hydration is Key While GLP-1s reduce appetite, they also reduce thirst, increasing risk of dehydration
While caution should be exercised, as this comparison is based on separate studies, this finding, if correct, may indicate a more important effect of GLP-1 in these areas in primates, including humans (86)
All patients had a minimum of two years of follow-up, and those with prior cognitive disorders or mixed treatment histories were excluded to strengthen the comparison
Accelerated production and regulatory approvals will help drive demand for oral semaglutide
Semaglutide mimics the action of natural GLP-1 in your body