@mvaduganathan @JavedButler1 @lamcardio @AndrewJSauer @SJGreene_md @gcfmd @DrMarthaGulati @hvanspall @dranulala @BiykemB @hfcollaboratory @HFA_President @HFSA @GMCRosano jamanetwork.com/journals/jama/ Semaglutide and Tirzepatide in Patients With Heart Failure With Preserved Ejection Fraction In patients with cardiometabolic HFpEF, semaglutide and tirzepatide showed more than 40% risk reduction for the composite of hospitalization for heart failure or all-cause mortality compared with a placebo proxy
Headache, nasopharyngitis, upper respiratory tract infection, bronchitis, and joint pain (arthralgia) were reported in a lower proportion of subjects with SEM (0.5 mg and 1.0 mg) than with placebo
GLP-1 plays a critical role in appetite regulation, blood sugar balance, insulin secretion, and gastric emptying
Metformin is primarily used to manage blood glucose levels in people with type 2 diabetes and is also used off-label in individuals with prediabetes and in women with polycystic ovary syndrome (PCOS) who have insulin resistance
This guide covers mixing, calculating dosages, storage, and using PepFlow to prevent common errors
Researchers also found that patients with the MTHFR mutation, a gene variant associated with depression, may improve with methylfolate supplementation