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CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle

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Consistent with this, we also showed that exendin-4 suppressed GABAR-mediated the light-evoked inhibitory postsynaptic currents (L-IPSCs) of GCs via GLP-1Rs

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(6) Complex I in the regulation of ferroptosis Complex I: a context-dependent regulator of ferroptosis Complex I (NADH:ubiquinone oxidoreductase), the primary entry point of electrons into the mitochondrial ETC, has been implicated in ferroptosis regulation through its involvement in maintaining the redox state of CoQ 10