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Metformin is a lower-cost option compared to GLP-1 medications, suitable for those seeking modest weight loss or who dont qualify for or prefer to avoid GLP-1 drugs and needles

Rheumatoid arthritis requires prompt rheumatology referral and disease-modifying drugs such as methotrexate, with biological therapies for refractory cases

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The safety profile of semaglutide was comparable to that reported in the recent phase 3 trial with once-weekly dosing in patients with obesity and trials from the SUSTAIN (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) programs[14,35]

The risk of developing melanoma is 20 times higher for whites (1 in 38) than Hispanics (1 in 172) and African Americans (1 in 1000)

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