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Efpeglenatide is a long-acting GLP-1RA, which was developed for the management of hyperglycemia in patients with T2D [50]

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This was highlighted in an experimental study performed on GLP-1-treated HL-1 cardiomyocytes, in which GLP1 increased calcium transients and sarcoplasmic reticular calcium contents by regulating the expression of calcium handling proteins, leading to a reduced calcium leak and thus preventing AF development [34]