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Mosenzon O, Del Prato S, Schechter M, Leiter LA, Ceriello A, DeFronzo RA, et al

Obesity and physical inactivity have been identified as the two most important modifiable risk factors for diabetes, factors that can be changed through lifestyle intervention

(3) FEBS Lett

Furthermore, considering emotional well-being is crucial, as psychological factors like stress, anxiety, depression, or disordered eating patterns can impact physical health

Microvasc Res 92:7984

Effective glucose control in patients with T2DM has demonstrated a modest impact on CV benefit in the past, but the negative effects of rosiglitazone on CV outcomes in some studies [5] had resulted in the Food and Drug Administration (FDA) mandate all new glucose-lowering medications to verify CV safety and mortality