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What little human research that does exist has been promising, but inconclusive: One review of 12 studies showed that berberine treatment reduced body weight, waist circumference, body mass index (BMI), and CRP (C-reactive protein)levels

doi: 10.3389/FMICB.2021.750460 130 PahlevanzadehF.SetayeshmehrM.Bakhsheshi-RadH

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Severe vomiting or diarrhoea can also lead to dehydration and potential kidney problems, particularly in vulnerable patients