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We were unable to test treatments containing gemcitabine in the 3D set-up, because prolonged incubation with gemcitabine (necessary for invasion studies through collagen matrices), resulted in the death of all tumour cells on the top of the 3D matrix

As the first oral formulation in this drug class, it offers an alternative to injectable GLP-1 agonists whilst maintaining similar efficacy in glycaemic control

J Chem Neuroanat 36(2):107121 Ciofi P et al (2009) Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus

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For instance, dysbiosis has the potential to lead to T cell population alterations, which in turn may produce a tipping in the balance towards systemic autoimmunity

PDZ, proteins containing PDZ domain