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While the inflammation-reducing and fibrosis-attenuating effects of glucagon agonism are less well-characterized, the reductions in hepatic inflammation parameters and fibrosis observed in preclinical models likely reflect secondary effects consequent to improved steatosis, rather than direct anti-inflammatory actions [21]

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Yet, health care spending is on the rise, up eight percent year-over-year per individual employee, according to the 2026 Milliman Medical Index

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People experiencing significant GI side effects that might cause dehydration

All subjects received nutritional counseling from clinical research nutritionists at baseline, six months and 12 months